Synthesis and Characterization of Some Novel Mannich Base Compounds

Authors

Sounthari P
Assistant Professor, Department of Chemistry,PSG College of Arts and Science, Coimbatore-641 014.
https://orcid.org/0000-0002-0304-5576
Sivakumar P.R
PG& Research Department of Chemistry, Government Arts College (Autonomous), Coimbatore - 641 018, Tamil Nadu, India.
https://orcid.org/0000-0001-7182-9658

Keywords:

Mannich Base Compounds, Corrosion

Synopsis

The present study includes Synthesis of new Mannich base compounds based on some 1, 3, 5-triazine substituted uracil derivatives with formaldehyde and secondary amines. The title compounds were screened for their in vitro antimicrobial activity against Bacillus subtitle, Pseudonomous Aeruginosa, Staphylococcus aureoles and E.Colli and three fungal species Aspergillus niger, Candida Albicans and Aspergillus fumigatus using the disc diffusion method. Most of the synthesized compounds appeared with promising antimicrobial and antioxidant activity. The structure of the novel compounds were elucidated on the basis of IR, 1H and 13C NMR spectroscopy.

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Published

December 9, 2019

Details about this monograph

ISBN-13 (15)

978-93-89631-04-3