Synthesis and Characterization of Some Novel Mannich Base Compounds
The present study includes Synthesis of new Mannich base compounds based on some 1, 3, 5-triazine substituted uracil derivatives with formaldehyde and secondary amines. The title compounds were screened for their in vitro antimicrobial activity against Bacillus subtitle, Pseudonomous Aeruginosa, Staphylococcus aureoles and E.Colli and three fungal species Aspergillus niger, Candida Albicans and Aspergillus fumigatus using the disc diffusion method. Most of the synthesized compounds appeared with promising antimicrobial and antioxidant activity. The structure of the novel compounds were elucidated on the basis of IR, 1H and 13C NMR spectroscopy.
Review of Literature
Materials and Methods
Results and Discussion
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